From: Search strategies to identify reports on “off-label” drug use in EMBASE
Search query | Cumulative number of relevant records retrieved | Cumulative number of records retrieved | Cumulative sensitivity/full set (%) | Cumulative sensitivity/EMBASE set (%) | Cumulative Precision (%) | |
---|---|---|---|---|---|---|
1 | off label*.af. | 3150 | 3577 | 77.45 | 81.90 | 88.06 |
2 | (off adj1 label).mp. | 3152 | 3581 | 77.50 | 81.96 | 88.02 |
3 | (drug adj2 label adj2 us*).af. | 3153 | 3617 | 77.53 | 81.98 | 87.17 |
4 | unlicense*.af. | 3279 | 4320 | 80.62 | 85.26 | 75.90 |
5 | unapprove*.af. | 3445 | 4635 | 84.71 | 89.57 | 74.33 |
6 | (label adj3 indication*).af. | 3450 | 4667 | 84.83 | 89.70 | 73.92 |
7 | off li?en?e*.af. | 3509 | 4742 | 86.28 | 91.24 | 74.00 |
8 | ((no* licen?ed for adj3 use*) not now licen?ed).af. | 3560 | 4825 | 87.53 | 92.56 | 73.78 |
9 | ((inappropriate us* and indication) not (antibiotic* or antimicrobial)).af. | 3609 | 4964 | 88.74 | 93.84 | 72.70 |
10 | ((appropriate* adj3 prescri*) and indication).af. | 3648 | 5081 | 89.70 | 94.85 | 71.80 |
11 | (outside adj3 licen?e*).af. | 3665 | 5110 | 90.12 | 95.29 | 71.72 |
12 | unlabel* us*.af. | 3692 | 5140 | 90.78 | 96.00 | 71.83 |
13 | labeled indication*.af. | 3703 | 5169 | 91.05 | 96.28 | 71.64 |
14 | (inappropriate indication*).af. | 3719 | 5294 | 91.44 | 96.70 | 70.25 |
15 | nonapprove*.af. | 3737 | 5337 | 91.89 | 97.17 | 70.02 |
16 | registered indication*.af. | 3752 | 5367 | 92.25 | 97.56 | 69.91 |
17 | offlabel*.af. | 3757 | 5372 | 92.38 | 97.69 | 69.94 |
18 | (out* adj4 licen?ed indication*).af. | 3759 | 5376 | 92.43 | 97.74 | 69.92 |
19 | (unlabel* adj3 indication*).af. | 3767 | 5384 | 92.62 | 97.95 | 69.97 |
20 | non fda approve*.af. | 3780 | 5411 | 92.94 | 98.28 | 69.86 |
21 | ((no* licen?ed for adj3 indication*) not now licen?ed).af. | 3793 | 5425 | 93.26 | 98.62 | 69.92 |
22 | (appropriate indication adj3 us*).af. | 3796 | 5432 | 93.34 | 98.70 | 69.88 |
23 | (be???d* adj2 licen?ed indication*).af. | 3799 | 5436 | 93.41 | 98.78 | 69.89 |
24 | (us* without adj2 indication*).af. | 3804 | 5445 | 93.53 | 98.91 | 69.86 |
25 | (prescri* outside adj4 guideline*).af. | 3808 | 5450 | 93.63 | 99.01 | 69.87 |
26 | (out of label).af. | 3810 | 5466 | 93.68 | 99.06 | 69.70 |
27 | (improper adj1 indication*).af. | 3812 | 5472 | 93.73 | 99.12 | 69.66 |
28 | (inappropriate adj5 indication adj2 us*).af. | 3814 | 5475 | 93.78 | 99.17 | 69.66 |
29 | no* appropriate indication*.af. | 3815 | 5482 | 93.80 | 99.19 | 69.59 |
30 | (non evidence base* us*).af. | 3818 | 5487 | 93.88 | 99.27 | 69.58 |
31 | without proper indication*.af. | 3821 | 5498 | 93.95 | 99.35 | 69.50 |
32 | (or/1-31) or (drug* without adj2 indication*).af. | 3822 | 5501 | 93.98 | 99.38 | 69.48 |