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Table 3 Differences in concomitant treatments between groups

From: Are concomitant treatments confounding factors in randomized controlled trials on intensive blood-glucose control in type 2 diabetes? a systematic review

 

Intensive (%)

Standard (%)

P value

ADVANCE [17]

   

-Antihypertensive drugs

88.9

88.4

0.44

-Statins

45.6

47.7

0.09

-Other cholesterol-lowering drugs

7

7

0.90

-Aspirin

57

54.9

0.02

-Other anti-aggregating drugs

7.1

6.2

0.07

ACCORD [18]

   

-Anti-hypertensive drugs

91

92

0.06

-ACEIs

69.7

71.9

0.02

-Beta blockers

47.5

48.6

0.27

-Statins

88

87.6

0.54

-Aspirin

75.5

75.5

0.98

Kumamoto [16]

11

11

1

-Statins

3.6

5.4

0.66

-Fibrates

0

0

-

-Aspirin

1.8

3.6

0.60

- Antiplatelet therapy

12.7

18.1

0.45

-ACEI

0

 

-

-ARB

   
  1. ACEI angiotensin-converting enzyme inhibitors.
  2. ARB angiotensin-receptor blockers.