Table 3 Suggested approaches from COG and CCL that would facilitate accrual at the institutions
Themes and sub-themes (number of times mentioned) | Example quotations |
|---|---|
Staff presence and dynamics (2) | |
Awareness (2) | "Encourage newer COG CRA and RN members to participate." |
Logistics including adequate numbers of eligible patients (14) | |
Ensure study is feasible and minimize data collection (6) | "Simplify, simplify, simplify! Distill CRFs down to the bare minimum data needed to answer the study aims." |
Email reminder for eligible patients (5) | "It would be really helpful to have email alerts." |
"Email reminders about patients who have been flagged as potentially eligible can be helpful." | |
Broaden eligibility (3) | "Keep requirements to a minimum." |
"(…) more CCL trials for disease sites that do not currently have a treatment trial." | |
Interests and priorities (2) | |
Patient potential benefit (1) | "Data that shows outcomes of patients enrolled on CCL studies would generate enthusiasm from staff." |
Patient incentives (1) | "Patients always like incentives for participation." |
Resources (30) | |
Support from CCL committee (13) | "I think the committee members/protocol staff members are extremely responsive, supportive, and never leave us hanging." |
Funding (12) | "Increased per case reimbursement." |
"Have it count as a therapeutic trial for payment/accrual." | |
Information provision (4) | "CCL study sessions at COG Fall Meeting (…) was extremely helpful to learn from what worked and what didn't work at other sites. It demystified a lot of my apprehensions in opening the study at my institution." |
"Have a meeting with all the lead CRAs and review protocols that are available and ask for input." | |
Centralized CCL staff (1) | "Provide a CCL centralized staff that do the regulatory for CCL protocols remotely and abstract and submit the data either remotely or otherwise." |