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Table 2 Participant characteristic by baseline statin use

From: Using imputed pre-treatment cholesterol in a propensity score model to reduce confounding by indication: results from the multi-ethnic study of atherosclerosis

 

Baseline statin use

 

Non-weighted

Weighted using stabilized IPTW1

Characteristics

  No (N = 5150)

  Yes (N = 885)

 

  No (N = 5150)

  Yes (N = 885)

 
 

Mean (SD) or n (%)

Mean (SD) or n (%)

P-value

Mean (SD) or n (%)

Mean (SD) or n (%)

P-value

Age, Mean (SD), y

61.3 (10.3)

65.9 (8.8)

<.001

62.0 (10.2)

62.9 (9.7)

0.141

Male

2441 (47.4%)

417 (47.1%)

0.879

2530 (47.7%)

401 (50.8%)

0.308

Race/ethnicity

      

White

1976 (38.4%)

385 (43.5%)

0.004

2069 (39.0%)

351 (44.5%)

0.156

Chinese

672 (13.1%)

99 (11.2%)

 

650 (12.3%)

74 (9.4%)

 

Black

1323 (25.7)

235 (26.6%)

 

1355 (25.6%)

186 (23.6%)

 

Hispanic

1179 (22.9%)

166 (18.8%)

 

1226 (23.1%)

178 (22.6%)

 

Body mass index, kg/m2

28.1 (5.5)

28.7 (5.0)

<.001

28.2 (5.4)

28.5 (5.2)

0.235

Current smoker

690 (13.4%)

83 (9.4%)

0.001

659 (12.4%)

84 (10.6%)

0.394

Pack years smoking

11.0 (22.3)

12.9 (22.4)

0.021

11.1 (22.2)

10.9 (21.5)

0.880

Current alcohol use

2902 (56.4%)

507 (57.3%)

0.603

2997 (56.5%)

479 (60.7%)

0.128

Diabetes

534 (10.4%)

191 (21.6%)

<.001

729 (13.8%)

(111 (14.0%)

0.897

Family history of MI

1952 (37.9%)

427 (48.3%)

<.001

2153 (59.4%)

334 (42.4%)

0.542

Hypertension

2082 (40.4%)

543 (61.4%)

<.001

2301 (43.4%)

358 (45.3%)

0.492

Hypertension Meds

1645 (32.0%)

520 (58.8%)

<.001

1941 (36.6%)

309 (39.2%)

0.323

Total cholesterol, mg/dL

196.7 (35.7)

224.1 (36.4)

<.001

206.4 (50.9)

204.4 (41.2)

0.611

Systolic BP, mm Hg

125.5 (21.3)

129.7 (21.6)

<.001

126.1 (21.1)

127.3 (22.3)

0.286

Diastolic BP, mm Hg

72.0 (10.4)

71.2 (9.6)

0.038

71.9 (10.3)

72.0 (9.9)

0.727

Health insurance

4644 (90.2%)

861 (97.3%)

<.001

4789 (90.4%)

741 (93.9%)

0.109

Income

      

<$25 K

1586 (30.8%)

285 (32.2%)

0.165

1679 (31.7%)

229 (29.0%)

0.592

$25 K-$49 K

1492 (29.0%)

250 (28.3%)

 

1558 (29.4%)

237 (30.0%)

 

$50 K-$99 K

1375 (26.7%)

212 (24.0%)

 

1351 (25.5%)

198 (25.1%)

 

$100 K+

697 (13.5%)

138 (15.6%)

 

712 (13.4%)

125 (15.9%)

 

Education

      

< High school

914 (17.8%)

143 (16.2%)

0.164

941 (17.8%)

124 (15.7%)

0.381

High school

2352 (45.7%)

420 (47.5%)

 

2475 (46.7%)

366 (46.4)

 

College

937 (18.2%)

142 (16.1%)

 

914 (17.3%)

124 (15.8%)

 

Graduate school

947 (18.4%)

180 (20.3%)

 

970 (18.3%)

174 (22.1%)

 

Married

3160 (61.4%)

546 (61.7%)

0.850

3246 (61.3%)

502 (63.6%)

0.406

Intentional exercise (met-min/wk)

1583 (2396)

1527 (2130)

0.480

1644 (2421)

1692 (2477)

0.705

Creatinine, mg/dL

0.94 (0.23)

1.01 (0.41)

<.001

0.97 (0.31)

0.97 (0.30)

0.778

Fibrinogen, mg/dL

342.6 (72.8)

357.4 (74.6)

<.001

351.3 (83.8)

356.4 (88.0)

0.530

hs-CRP, mg/L

3.7 (5.8)

3.2 (4.8)

0.004

3.6 (5.4)

4.2 (7.3)

0.396

CAC (Agatston)

122 (367)

240 (522)

<.001

149 (400)

161 (444)

0.525

Common carotid (mm)

0.86 (0.19)

0.91 (0.19)

<.001

0.87 (0.19)

0.88 (0.19)

0.195

Internal carotid (mm)

1.03 (0.57)

1.25 (0.67)

<.001

1.08 (0.61)

1.13 (0.66)

0.139

Heart rate (bpm)

63.0 (9.5)

63.6 (9.8)

0.066

63.3 (9.8)

63.8 (10.4)

0.455

  1. 1 Comparisons for the first imputation.