Figure 5From: Matching methods to create paired survival data based on an exposure occurring over time: a simulation study with application to breast cancer Methods and Models. Exposure effect’s estimation according to Methods 1 and 2 and related to: (A) The HP model, (B) The L W A u model, (C) The L W A a model and (D) The L W A i model. The solid thick lines red, blue and green (Figure A, B and C) respectively, represent the theoretical average of γ(t) and the solid thick orange lines (Figure D) represent the theoretical γ(t)+ α ′ (t)Z inside each profile Z. The fine lines red, blue and green (Figure A, B and C) respectively, represent γ(t), estimated according to Methods 1 (fine dotted lines) and 2 (solid dotted lines); and the fine red lines (Figure D) represent the observed γ(t)+ α ′ (t)Z inside each profile. The average bias and RMSE are given for each model: b l•, b ••, R M S E l• and R M S E ••. These results are obtained with the increasing then decreasing H R(t) configuration, without censoring and with β 12 ′ =(−0.2,−0.4,−0.8), β 13 =− β 12 and β 23 =− β 13 .Back to article page