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Table 1 The primary and secondary aims of DIAMOND

From: Pragmatic trials in primary care. Methodological challenges and solutions demonstrated by the DIAMOND-study

Primary aim of DIAMOND:

• To investigate which treatment strategy, "step-up" or "step-down" treatment, was the most (cost-)effective initial management strategy for patients with a new episode of dyspepsia in primary care.

Secondary aims of DIAMOND:

• To investigate which factors influence the severity of the GI complaints.

• To investigate which factors determine compliance with dyspepsia medication prescriptions and compliance with advised lifestyle changes.

• To investigate which factors influence treatment success.

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BMC Medical Research Methodology

ISSN: 1471-2288

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