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Table 2 Estimated correlation coefficients and their 95% confidence intervals in the random intercepts and random slopes, from the primary analysis and three sensitivity analyses using bivariate linear mixed models

From: Estimating correlation between multivariate longitudinal data in the presence of heterogeneity

Models

Correlations between random intercepts

Correlations between random slopes

Primary analyses: without adjusting heterogeneity

0.278 (0.121, 0.420)

0.579 (0.349, 0.810)

Sensitivity #1: adjusting the severity of vision damage at diagnosis (MD < −5 dB vs. MD ≥ −5 dB)

0.267 (0.090, 0.452)

0.519 (0.285, 0.753)

Sensitivity #2: excluding those who labelled as “Rapid Progression”.

0.217 (0.077, 0.354)

0.289 (0.010, 0.593)

Sensitivity #3: estimating class-specific intercepts and slopes

0.145 (−0.037, 0.324)

0.106 (−0.255, 0.490)