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Fig. 4 | BMC Medical Research Methodology

Fig. 4

From: A Bayesian approach to pilot-pivotal trials for bioequivalence assessment

Fig. 4

Comparison between the proposed method and conventional CI method in terms of the statistical power, i.e., probability of correctly declaring bioequivalence (%) on the completion of a pivotal trial, using C\(_\text {max}\) data. Pilot data are simulated based on the scenarios of GMR = 1.0, while pivotal data are simulated under Cases A - E with GMR = 0.8, 0.9, 1.0, 1.1, 1.25, respectively

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