Table 1 ADePT-DDR dose-levels and duration of treatment for AZD6738
Dose Level | AZD6738 Daily dose (mg BD) | Weeks | Duration (days) | Radiotherapy |
|---|---|---|---|---|
-1 | 20 | 1 | 5 | 70 Gy/ 35 F |
0 | 20 | 1 &4 | 10 | 70 Gy/ 35 F |
1 | 40 | 1 &4 | 10 | 70 Gy/ 35 F |
2a | 40 | 1,2,4 &5 | 20 | 70 Gy/ 35 F |
2b | 80 | 1 &4 | 10 | 70 Gy/ 35 F |
3 | 120 | 1 &4 | 10 | 70 Gy/ 35 F |
80 | 1,2,4 &5 | 20 | 70 Gy/ 35 F |