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Featured article: Definition of a systematic review used in overviews of systematic reviews, meta-epidemiological studies and textbooks

Definitions for systematic reviews are ambiguous. This publication suggests a more specific definition and aims to motivate the research community to establish a clear guideline.

Featured article: Purposive sampling in a qualitative evidence synthesis

In a qualitative evidence synthesis, too much data can undermine the ability to perform a thorough analysis. Purposive sampling of primary studies for inclusion in the synthesis is one way to overcome this. In this highly accessed article, the authors describe the development and application of a sampling framework for a qualitative evidence synthesis on vaccination communication.


  1. Authors: Lehana Thabane, Jinhui Ma, Rong Chu, Ji Cheng, Afisi Ismaila, Lorena P Rios, Reid Robson, Marroon Thabane, Lora Giangregorio and Charles H Goldsmith

    Content type: Commentary

  2. Authors: Sarah Crowe, Kathrin Cresswell, Ann Robertson, Guro Huby, Anthony Avery and Aziz Sheikh

    Content type: Commentary

Aims and scope

BMC Medical Research Methodology is an open access journal publishing original peer-reviewed research articles in methodological approaches to healthcare research. Articles on the methodology of epidemiological research, clinical trials and meta-analysis/systematic review are particularly encouraged, as are empirical studies of the associations between choice of methodology and study outcomes. BMC Medical Research Methodology does not aim to publish articles describing scientific methods or techniques: these should be directed to the BMC journal covering the relevant biomedical subject area.


Section Editors

Meet the editors

Livia Puljak, MD, PHD is professor at the University of Split School of Medicine in Split, Croatia. Her research interests are focused on methods in evidence-based medicine, clinical epidemiology and pain. She joined BMC Medical Research Methodology as Section Editor 2018.

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