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Table 2 Comparison between review results for nicotine patch in 1994 and 2000

From: Updating a systematic review – what difference did it make? Case study of nicotine replacement therapy

  Review year 1994 2000
a) All trials No. of trials 9 30
  Odds ratio 2.07 1.73
  95% CI 1.64–2.62 1.56–1.93
  Χ2 & p for heterogeneity 7.08 (p = 0.53) 41.75(p = 075)
b) Level of support sub group: No. of trials 4 12
-Low intensity Odds ratio 2.52 1.74
  95% CI 1.64–3.87 1.48–2.04
  Χ2 & p for heterogeneity 4.84(p = 0.18) 18.69(p = 0.096)
-High intensity No. of trials 5 18
  Odds ratio 1.99 1.73
  95% CI 1.49–2.64 1.51–1.99
  Χ2 & p for heterogeneity 2.55 (p = 0.64) 23.06 (p = 0.15)
c) Length of follow-up subgroups: No. of trials 3 11
-6 months Odds ratio 1.96 1.96
  95% CI 1.44–2.66 1.65–2.34
  Χ2 & p for heterogeneity 1.74(p = 0.72) 8.06 (p = 0.62)
-12 months No. of trials 6 19
  Odds ratio 2.09 1.62
  95% CI 1.39–3.12 1.42–1.84
  Χ2 & p for heterogeneity 2.38 (p = 0.67) 30.67 (p = 0.044)