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Table 3 Parameter estimates in models for DEH11 and EPI8 for all subjects (analysis data set)

From: Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers

a) Model for DEH11

R2= 0.29

Parameters

Value.

Std Error

t value

P value

Intercept

-4045.3022

752.258

-5.38

<0.001

COTIN.IFGT.11

1.4494

0.123

11.78

<0.001

UCRCAL.IFLT.3036

0.3531

0.0484

7.30

<0.001

CRCL.IFLT.4325

0.3698

0.0391

9.45

<0.001

AST.IFGT.25

17.9064

1.2832

13.95

<0.001

AST.IFGT.126

-18.2428

2.3656

-7.71

<0.001

ALKPH.IFLT.184

3.1360

0.6583

4.76

<0.001

ALKPH.IFGT.184

30.7979

3.6627

8.41

<0.001

NSAID.EQ.YES

-346.0560

38.2528

-9.05

<0.001

VITAMIN.EQ.YES

-211.7183

29.8500

-7.09

<0.001

b) Model for EPI8

R 2 = 0.41

Parameters

Value.

Std Error

t value

P value

Intercept

1383.0200

574.483

2.41

0.016

TOTNN.IFLT.57

5.1813

0.7683

6.74

<0.001

TOTNN.IFGT.57

0.5548

0.0593

9.35

<0.001

TOTNN.IFGT.1452

-1.4595

0.3895

-3.75

0.000

OHP.IFLT.473

0.8552

0.1212

7.05

<0.001

CRCL

0.6268

0.0262

23.93

<0.001

AST.IFGT.22

-135.4800

30.5048

-4.44

<0.001

AST.IFGT.24

247.4960

59.5308

4.16

<0.001

AST.IFGT.26

-108.4000

33.1568

-3.27

0.001

AST.IFLT.106

12.2512

2.2425

5.46

<0.001

WEIGHTK

6.2845

0.7274

8.64

<0.001

VITAMIN.EQ.YES

-250.7700

28.4736

-8.81

<0.001