Skip to main content
Figure 5 | BMC Medical Research Methodology

Figure 5

From: Estimates of sensitivity and specificity can be biased when reporting the results of the second test in a screening trial conducted in series

Figure 5

Effect of proportion of double negative cases on percent bias. Effect of the proportion of double negative cases on percent bias in observed sensitivity (A) and specificity (B). Note that the scale of the y-axis of the specificity graph (B) is enlarged to show minute changes. Parameter definitions are as in "Parameters" (Table 6), except that the proportion double negative cases is allowed to vary. Otherwise as Figure 3.

Back to article page