Table 6 Group 1 (trekkers) (n = 198) - Testing performed at each laboratory

Subjects at laboratory

198

198

197

195

190

CORE STUDIES

Daily diary

198

195

196

194

190

CPX Ramp (+NIRS)

190*

189

184

183

153

CPX ME

195**

n/a

191

n/a

164

Spirometry

198

197

190

176

185

Venesection

198

198

195

194

181

Neurocognitive

198

160 (on return)

195

n/a

185

Pupillometry

198

n/a

191

n/a

186

Cranial measurements

198

n/a

n/a

n/a

n/a

Retinal photography

183

n/a

n/a

n/a

183

Plasma biomarkers

198

198

195

194

181

ADDITIONAL STUDIES

Hypoxic Pulmonary Vasoconstriction

31 screened13 selected

n/a

11

n/a

11

Smell and taste

59

n/a

n/a

n/a

59

Sleep

n/a

n/a

n/a

n/a

15

Oxygen Delivery Circuit

n/a

n/a

n/a

n/a

6

Cardiac MRI and 31P-MRS

7

n/a

n/a

n/a

n/a

Skeletal Muscle MRI and 31P-MRS[23]

7

n/a

n/a

n/a

n/a

Structural and Volumetric MRI Study

7

n/a

n/a

n/a

n/a