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Table 6 Group 1 (trekkers) (n = 198) - Testing performed at each laboratory

From: Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia

  Sea Level Kathmandu
(1300 m)
Namche
(3500 m)
Pheriche
(4250 m)
EBC
(5300 m)
Subjects at laboratory 198 198 197 195 190
CORE STUDIES      
Daily diary 198 195 196 194 190
CPX Ramp (+NIRS) 190* 189 184 183 153
CPX ME 195** n/a 191 n/a 164
Spirometry 198 197 190 176 185
Venesection 198 198 195 194 181
Neurocognitive 198 160 (on return) 195 n/a 185
Pupillometry 198 n/a 191 n/a 186
Cranial measurements 198 n/a n/a n/a n/a
Retinal photography 183 n/a n/a n/a 183
Plasma biomarkers 198 198 195 194 181
ADDITIONAL STUDIES
Hypoxic Pulmonary Vasoconstriction 31 screened13 selected n/a 11 n/a 11
Smell and taste 59 n/a n/a n/a 59
Sleep n/a n/a n/a n/a 15
Oxygen Delivery Circuit n/a n/a n/a n/a 6
Cardiac MRI and 31P-MRS 7 n/a n/a n/a n/a
Skeletal Muscle MRI and 31P-MRS[23] 7 n/a n/a n/a n/a
Structural and Volumetric MRI Study 7 n/a n/a n/a n/a
  1. * 6 subjects withdrawn from incremental CPET prior to departure and 2 because of poor baseline data quality
  2. ** 3 subjects withdrawn from efficiency CPET prior to departure