| Gluud [17] | Kjaergard [16] | Current study | Kjaergard [18] | Bai [15] | Current study |
---|---|---|---|---|---|---|
Study period | 1985-1997 | 1981-1998 | 1998 | 1964-2000 | 2006 | 2008 |
Included journals | the Journal of Hepatology | Hepatology | 5 * | Gastroenterology | 6* | 5* |
Number of RCTs | 166 | 235 | 99 | 383 | 105 | 107 |
Sequence generation | 47(28%) | 121(51%) | 35(35%) | 161(42%) | 85(81%) | 81(76%) |
Allocation concealment | 22(13%) | 80(34%) | 25({25%) | 149(39%) | 64(61%) | 62(58%) |
Blinding | 50(30%) | 80(34%) | 52(53%) | 237(62%) | 54(51%) | 62(58%) |
Sample size calculation | 33(20%) | 61(26%) | 47(47%) | - | 79(75%) | 83(78%) |
Incomplete outcome | - | 165(70%) | 34(34%) | - | - | 52(49%) |
Intention-to-treat analysis | 95(57%) | - | 42(42%) | - | - | 74(69%) |
Free of selective reporting | - | - | 43(43%) | - | - | 57(53%) |