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Table 4 Minimally Important Difference (MID), standard error of measurement (SEM) and effect size of the standardised SATMED-Q total and domain scores calculated for the sample of 456 patients to test psychometric properties of the instrument

From: Minimally important difference of the Treatment Satisfaction with Medicines Questionnaire (SATMED-Q)

     Distribution-based MID   
SATMED-Q domain SATMED-Q mean score at neutral satisfaction category of TSQM item #14 SATMED-Q mean score at satisfied/dissatisfied category of TSQM item #14 Anchor-based MID1 SEM2 One-half SD    Effect size3
Treatment effectiveness 51.5 (20.8) 67.1 (19.9) 15.6 9.5 10.9    0.71
Convenience of use 57.8 (26.3) 72.9 (21.1) 15.1 8.6 11.6    0.65
Impact on daily living/activities 43.5 (21.3) 64.1 (22.3) 20.6 9.4 12.2    0,85
Medical care 69.9 (22.3) 80.1 (17.8) 10.3 8.1 11.9    0.43
General satisfaction 57.1 (22.2) 75.2 (19.0) 18.2 8.1 10.6    0.83
Undesirable side effects 76.5 (24.4) 88.0 (20.8) 11.5 5.9 10.0    0.58
Total score 59.3 (12.1) 72.7 (13.0) 13.4 5.9 7.4    0.91
  1. Values are means (standard deviation). 1Computed as the raw difference between scores in neutral response and satisfied/dissatisfied categories of TSQM item #14 used as an anchor reference. 2 SEM = Standard error of measurement obtained by multiplying the standard deviation of each domain or the total score in the entire sample by the root square of 1 minus the coefficient of reliability (-Cronbach's α). 3Obtained by dividing the MID of the domain or total score by the standard deviation of the whole sample for that domain or total score. TSQM = Treatment Satisfaction Questionnaire for Medications. SATMED-Q = Satisfaction with Medicines Questionnaire. SD = standard deviation.