| Stage I (n = 14)a | Stage IIa | Stage I Stop? | Drug Activity | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Trial | Res | Prog | Resp | Prog | Gehan | DESR epd0.4/0.6 | DESR epd0.3/0.5 | Gehan | DESR epd0.4/0.6 | DESR epd0.3/0.5 |
1 | 0 | 14 | 0/23 | 20/23 | Y | Y | Y | N | N | N |
2 | 0 | 10 | 0/24 | 18/24 | Y | Y | Y | N | N | N |
3 | 0 | 9 | 0/17 | 10/17 | Y | Y | Y | N | N | N |
4 | 0 | 8 | 0/36 | 23/36 | Y | Y | Y | N | N | N |
5 | 0 | 11 | 0/19 | 14/19 | Y | Y | Y | N | N | N |
6 | 0 | 13 | 0/23 | 20/23 | Y | Y | Y | N | N | N |
7 | 0 | 11 | 0/15 | 12/15 | Y | Y | Y | N | N | N |
8 | 0 | 11 | Â | Â | Y | Y | Y | N | N | N |
9 | 1 | 12 | 2/34 | 23/34 | N | Y | Y | N | N | N |
10 | 1 | 8 | 2/27 | 16/27 | N | Y | Y | N | N | N |
11 | 1 | 10 | 1/19 | 12/19 | N | Y | Y | N | N | N |
12 | 1 | 10 | 2/25 | 17/25 | N | Y | Y | N | N | N |
13 | 1 | 10 | 1/20 | 15/20 | N | Y | Y | N | N | N |
14 | 1 | 9 | 1/17 | 11/17 | N | Y | Y | N | N | N |
15 | 1 | 12 | 1/18 | 16/18 | N | Y | Y | N | N | N |
16 | 4 | 9 | 7/29 | 14/29 | N | N | N | Y | Y | Y |
17 | 8 | 2 | 20/34 | 3/34 | N | N | N | Y | Y | Y |
18 | 5 | 4 | 7/32 | 13/32 | N | N | N | Y | Y | Y |
19 | 4 | 4 | 12/37 | 14/37 | N | N | N | Y | Y | Y |
20 | 4 | 3 | 7/30 | 11/30 | N | N | N | Y | Y | Y |
21 | 5 | 4 | 9/36 | 9/36 | N | N | N | Y | Y | Y |
22 | 3 | 4 | 6/27 | 10/27 | N | N | N | Y | Y | Y |
23 | 11 | 1 | 27/35 | 3/35 | N | N | N | Y | Y | Y |