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Table 1 List of the main variables, number of original studies and related subjects per variable

From: Melanocortin-1 receptor, skin cancer and phenotypic characteristics (M-SKIP) project: study design and methods for pooling results of genetic epidemiological studies

Variable

Studies (%) N = 39

Melanoma cases (%) n = 7806

NMSC cases (%) n = 3151

Controls (%) n = 14875

Age

37 (95%)

7761 (99%)

3150 (100%)

14550 (98%)

Gender

39 (100%)

7801 (100%)

3151 (100%)

14853 (100%)

Ethnicity

38 (97%)

6770 (87%)

3142 (100%)

13833 (93%)

Body mass index

8 (21%)

557 (7%)

1380 (44%)

2226 (15%)

Smoking status

6 (15%)

2266 (29%)

419 (13%)

2286 (15%)

Intermittent sun exposure

21 (54%)

4493 (58%)

1266 (40%)

2286 (15%)

Continuous sun exposure

21 (54%)

4909 (62%)

741 (24%)

1938 (13%)

Sunburns

25 (64%)

4210 (54%)

1288 (41%)

2968 (20%)

Artificial UV exposure

16 (41%)

3842 (49%)

298 (9%)

1058 (7%)

Family history of skin cancer

27 (69%)

6660 (85%)

1289 (41%)

3318 (22%)

Family history of cancer other than skin

19 (49%)

4445 (57%)

371 (12%)

1630 (11%)

Melanoma body site

24 (62%)

6271 (80%)

NA

NA

Melanoma histology

19 (49%)

4868 (62%)

NA

NA

Breslow thickness

24 (62%)

5907 (76%)

NA

NA

Hair color

34 (87%)

6841 (88%)

2590 (82%)

11889 (80%)

Eye color

31 (79%)

5990 (77%)

2456 (78%)

10720 (72%)

Skin color

23 (59%)

3517 (45%)

826 (26%)

2963 (20%)

Skin type

31 (79%)

6590 (84%)

1992 (63%)

4540 (31%)

Common nevi

19 (49%)

3817 (49%)

442 (14%)

1181 (8%)

Atypical nevi

11 (28%)

2681 (34%)

642 (20%)

1447 (10%)

Freckles

21 (54%)

4028 (52%)

737 (23%)

2333 (16%)

Solar lentigines

6 (15%)

1419 (18%)

442 (14%)

1088 (7%)

  1. NA = not applicable; NMSC = non melanoma skin cancer.