Temperature-mortality association in the North-East region of England, 1993–2006. Top-left: 3-D graph (with black reference line at 17°C). Top-right: predictor-specific summary at 22°C (red line parallel to the reference in the 3-D graph). Bottom-left: lag-specific summary at lag 4 (red line perpendicular to the reference in the 3-D graph). Bottom-right: overall cumulative summary. The 95%CI are reported as grey areas.