Cox model in | MRS in | |||||
---|---|---|---|---|---|---|
the FTR group | the STR group | |||||
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Variables entering in the model for FTR only | ||||||
Causal nephropathy (recurrent / non recurrent) | 1.24 | 0.96-1.59 | 0.0987 | - | - | - |
History of diabetes (positive / negative) | 1.34 | 0.96-1.85 | 0.0819 | - | - | - |
History of hypertension (positive / negative) | 0.77 | 0.57-1.05 | 0.0986 | - | - | - |
History of cardiac disease (positive / negative) | 1.41 | 1.11-1.79 | 0.0051 | - | - | - |
History of vascular disease (positive / negative) | 1.10 | 0.81-1.51 | 0.5351 | - | - | - |
History of dyslipemia (positive / negative) | 1.12 | 0.87-1.45 | 0.3828 | - | - | - |
History of hepatitis B/C (positive / negative) | 0.82 | 0.45-1.47 | 0.4969 | - | - | - |
History of malignancy (positive / negative) | 1.25 | 0.84-1.86 | 0.2698 | - | - | - |
Body mass index (≥ 30 kg.m-2 / < 30 kg.m-2) | 1.58 | 1.12-2.14 | 0.0084 | - | - | - |
Anti-class I PRA (positive / negative) | 1.45 | 1.07-1.97 | 0.0182 | - | - | - |
Anti-class II PRA (positive / negative) | 1.09 | 0.78-1.52 | 0.6299 | - | - | - |
Donor status (deceased/living) | 2.50 | 1.41-4.43 | 0.0016 | - | - | - |
Donor EBV serology (positive / negative) | 1.65 | 0.98-2.78 | 0.0606 | - | - | - |
Number of HLA-A-B-DR mismatches (> 4 / ≤ 4) | 1.30 | 0.97-1.76 | 0.0824 | - | - | - |
Induction therapy (depleting / non depleting) | 0.79 | 0.60-1.05 | 0.1091 | - | - | - |
Cold ischemia time (≥ 24 h / < 24 h) | 1.29 | 1.01-1.66 | 0.0441 | - | - | - |
Variables entering in both models | ||||||
Transplantation period (< 2005 / ≥ 2005) | 1.33 | 0.97-1.82 | 0.0693 | 0.97 | 0.55-1.74 | 0.9360 |
Recipient gender (male / female) | 1.17 | 0.91-1.51 | 0.2186 | 0.61 | 0.38-1.05 | 0.0720 |
Recipient age (≥ 55 years / < 55 years) | 1.39 | 1.05-1.83 | 0.0204 | 1.65 | 1.01-2.72 | 0.0480 |
Donor age (≥55 years / <55 years) | 1.34 | 1.03-1.74 | 0.0313 | 0.59 | 0.33-0.99 | 0.0440 |
Variables entering in the model for STR only | ||||||
Donor gender (male / female) | - | - | - | 1.53 | 1.03-2.48 | 0.0320 |
Waiting time before regraft ≥ 3 years | - | - | - | 1.92 | 1.22-3.00 | <0.0001 |