Table 3 Comparison of Cox proportional hazards model (Cox) and flexible parametric proportional hazards model (FPM), hazard ratios (95% confidence intervals)
From: Flexible parametric modelling of cause-specific hazards to estimate cumulative incidence functions
| Â | Breast cancer | Other cancer | ||
|---|---|---|---|---|
| Â | Cox | FPM | Cox | FPM |
Ages 18-59 | 1.00 | 1.00 | 1.00 | 1.00 |
Ages 60-69 | 0.90 (0.83, 0.97) | 0.90 (0.83, 0.98) | 2.12 (1.52, 2.94) | 2.12 (1.52, 2.95) |
Ages 70-79 | 1.27 (1.17, 1.37) | 1.27 (1.17, 1.37) | 3.18 (2.31, 4.37) | 3.19 (2.32, 4.38) |
Ages 80+ | 2.08 (1.90, 2.28) | 2.09 (1.91, 2.29) | 6.59 (4.73, 9.17) | 6.63 (4.76, 9.23) |
Localised | 1.00 | 1.00 | 1.00 | 1.00 |
Regional | 4.15 (3.85, 4.47) | 4.15 (3.85, 4.47) | 2.15 (1.61, 2.88) | 2.16 (1.61, 2.88) |
Distant | 33.68 (31.08, 36.50) | 33.84 (31.23, 36.67) | 25.58 (19.18, 34.12) | 25.82 (19.36, 34.44) |
| Â | Heart disease | Other causes | ||
| Â | Cox | FPM | Cox | FPM |
Ages 18-59 | 1.00 | 1.00 | 1.00 | 1.00 |
Ages 60-69 | 4.76 (3.62, 6.24) | 4.76 (3.62, 6.24) | 3.46 (2.89, 4.14) | 3.46 (2.89, 4.14) |
Ages 70-79 | 17.05 (13.42, 21.67) | 17.07 (13.43, 21.69) | 10.22 (8.73, 11.96) | 10.22 (8.73, 11.96) |
Ages 80+ | 70.57 (55.84, 89.17) | 70.75 (55.99, 89.40) | 31.54 (27.00, 36.84) | 31.60 (27.07, 36.91) |
Localised | 1.00 | 1.00 | 1.00 | 1.00 |
Regional | 1.42 (1.27, 1.60) | 1.42 (1.27, 1.60) | 1.11 (1.01, 1.26) | 1.11 (1.02, 1.22) |
Distant | 2.44 (1.89, 3.14) | 2.46 (1.91, 3.16) | 2.08 (1.67, 2.58) | 2.09 (1.68, 2.60) |