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Table 3 Comparison between the Cochrane review and this study in terms of scope and impact on P value in mortality

From: A systematic review and meta-analysis of acute stroke unit care: What’s beyond the statistical significance?

  OR (95% CI) P value
Present study - Primary analysis   
   Eight included trials (n = 8; Athens corrected*, Akershus, Goteborg- 0.84 (0.70 – 1.00) P = 0.05
   Sahlgren, Perth, Trondheim, Joinville, Edinburgh, Umea)
Present study - Secondary analysis   
    Inclusion of two unpublished trials 0.87 (0.74 – 1.03) P = 0.12
   (n = 10 ; Same as above plus Goteborg-Ostra, Svendborg)
    Inclusion of trials with very short-term observation 0.86 (0.74 – 1.01) P = 0.06
   (n = 12 ; Same as above plus Beijing, Stockholm)
   (i.e. All trials included in the Cochrane review, Athens corrected*)
The Cochrane review 2009   
    Cochrane review – Analysis 2.1 subtotal 0.85 (0.72 – 0.99) P = 0.03
   (n = 12; all trials mentioned above, Athens uncorrected)   
  1. * Number of deaths in the control arm was 121/302 instead of the 127/302 mentioned in the Cochrane Review 2009.