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Table 1 Baseline sociodemographic and clinical patient characteristics

From: Using the random forest method to detect a response shift in the quality of life of multiple sclerosis patients: a cohort study

 

Total sample°

N=580

Worsened patients*

N=107

Not-worsened patients*

p

Female, n (%)

 

419 (72.2)

75 (70.1)

300 (71.9)

0.71

Age (years)

M (SD)

41.3 (10.2)

43.2 (10.2)

40.9 (10.1)

0.03

 

Min, max

18, 71

19, 64

18, 69

 

Marital status, n (%)

Cohabiting/married

393 (67.8)

73 (68.2)

282 (67.6)

0.91

 

Divorced/separated/single/widowed

187 (32.2)

34 (31.8)

73 (68.2)

 

Employment status, n (%)

Employed

335 (57.8)

59 (55.1)

241 (57.8)

0.62

 

Unemployed/homemaker/retired/student

245 (42.2)

48 (44.9)

176 (42.2)

 

Educational level, n (%)

Elementary school

113 (19.5)

31 (28.4)

76 (18.2)

0.03

College

81 (14.0)

9 (8.3)

61 (14.6)

High school/university

386 (66.6)

67 (63.3)

280 (67.1)

EDSS score

M (SD)

2.9 (1.9)

3.5 (2.2)

2.8 (1.8)

<10 -3

Median

2.5

4.0

2.0

Min, max

0.0, 7.5

0.0, 7.0

0.0, 7.0

MS course, n (%)

Relapsing-remitting

510 (87.9)

79 (73.8)

381 (91.4)

<10 -3

Secondary progressive

53 (9.1)

18 (16.8)

30 (7.2)

Primary progressive

12 (2.1)

8 (7.5)

2 (0.5)

Primary relapsing

5 (0.9)

2 (1.9)

4 (1.0)

Time since first MS symptom (years)

M (SD)

10.0 (7.5)

10.2 (8.1)

9.9 (7.2)

0.73

 

Min, max

0, 45

0, 45

0.0, 40

 
  1. M (SD), mean (standard deviation);
  2. EDSS, Expanded Disability Status Scale; MS, multiple sclerosis;
  3. ° the 24-month EDSS was not available for 56 individuals.
  4. * defined as worsened or not-worsened based on change in EDSS score from baseline to month 24 according to the definition of Lublin [Lublin 1996] and Kappos [Kappos 2004];
  5. Bold values: p-value < 0.05.