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Table 3 Some methods for external validation and the level of information about the derivation study they require

From: External validation of a Cox prognostic model: principles and methods

  Method Aspect Information
    L1 L2 L3
1 Regression on PI in validation data D, F
2 Check model misspecification/fit F
3 Measures of discrimination D
4 Kaplan-Meier curves for risk groups D, C ×
5 Logrank/Cox tests between risk groups D ×
6 Hazard ratios across risk groups D ×
7 Calibration C × ×
  1. L1, L2 and L3 denote increasing amounts of information (see text). Key to Aspect: D, discrimination; C, calibration; F, model fit.