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Table 5 Acute myeloid leukemia: differences in the estimates of the log-hazard ratio when the combined model is fitted on the training (first column) or on the validation (second column) data

From: Added predictive value of omics data: specific issues related to validation illustrated by two case studies

 

Log-hazard ratios

Variable

Training

Validation

Omics score

0.642 (0.172)

0.523 (0.243)

Age (continuous)

0.021 (0.008)

0.022 (0.015)

Sex (male)

-0.024 (0.208)

0.643 (0.404)

FLT3-ITD

0.448 (0.253)

0.436 (0.440)

NPM1 (mutated)

-0.370 (0.215)

-0.377 (0.404)

  1. Standard deviations are reported between brackets.