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Table 3 Methods for handling missing data in sensitivity analysis in 27 trials

From: Handling missing data in RCTs; a review of the top medical journals

Sensitivity method Assumption Primary analysis Assumption N Total N (%)
Complete case MCAR Simple imputation MCAR 3 6 (22)
   MI MAR 2  
   Mixed Model MAR 1  
Simple imputation1 MCAR GEE MCAR 1 4 (15)
   MI MAR 1  
   Mixed model MAR 2  
GEE (un-weighted) MCAR Complete case MCAR 1 1 (4)
MI2 MAR Complete case MCAR 6 10 (37)
Simple imputation MCAR 1
GEE MCAR 1
Mixed model MAR 2
Mixed model MAR Complete case MCAR 2 2 (7)
Adjustment using auxiliary data MAR Mixed model MAR 2 2 (7)
Unclear   Complete case MCAR 1 2 (7)
Simple imputation MCAR 1
  1. 1One trial also performed complete case analysis.
  2. 2One trial also performed simple imputation.