Gender = male | Gender = female | |||||||
---|---|---|---|---|---|---|---|---|
Transition probability from | Time already spent in this stage (years) | To | Age = 20 | Age = 40 | Age = 60 | Age = 20 | Age = 40 | Age = 60 |
Compensated cirrhosis | < 1 | Death related to liver disease | 10.7% (8.3% - 13.0%) | 18.2% (13.9% - 22.5%) | 26.4% (19.9% - 32.8%) | 10.1% (7.4% - 12.8%) | 17% (12.9% - 21.1%) | 24.3% (18.2% - 30.3%) |
[8] | 1% | 1% | 1% | 1% | 1% | 1% | ||
Compensated cirrhosis | 1 - 10 | HCC | 17.1% (13.3% - 20.9%) | 25.1% (19.8% - 30.4%) | 33.8% (26.2% - 41.4%) | 16.8% (11.8% - 21.9%) | 23.6% (18.0% - 29.1%) | 30.9% (23.6% - 38.2%) |
[9] | 1% | 1% | 3% | 0.4% | 0.4% | 1.2% | ||
Compensated cirrhosis | >10 | HCC | 29.7% (22.2% - 37.2%) | 38.7% (30.0% - 47.4%) | 46.6% (37.4% - 55.8%) | 26.7% (19.1% - 34.3%) | 35.2% (26.5% - 44.0%) | 44.5% (34.7% - 54.3%) |
[9] | 2% | 2% | 4.5% | 0.6% | 0.6% | 1.8% | ||
First decompensation | ≤ 1 | Death related to liver disease | 20.3% (14.9% - 25.8%) | 29.1% (22.8% - 35.5%) | 39.4% (31.6% - 47.1%) | 18.0% (13.3% - 22.7%) | 25.9% (19.9% - 31.9%) | 34.6% (27.5% - 41.7%) |
[8] | 39% | 39% | 39% | 39% | 39% | 39% | ||
First decompensation | ≤ 1 | HCC | 28.7% (20.3% - 37.1%) | 37.2% (28.6% - 45.9%) | 47.0% (37.4% - 56.5%) | 26.2% (18.7% - 33.7%) | 32.9% (24.7% - 41.1%) | 39.5% (30.2% - 48.9%) |
Stable decompensated state* | Death related to liver disease | 21.6% (16.2% - 27.0%) | 29.9% (23.8% - 35.9%) | 39.2% (32.1% - 46.2%) | 20% (14.6% - 25.4%) | 27.5% (21.2% - 33.8%) | 35.4% (28.1% - 42.7%) | |
[8] | 12.5% | 12.5% | 12.5% | 12.5% | 12.5% | 12.5% | ||
Stable decompensated state* | 1 - 10 | HCC | 28.0% (21.5% - 34.4%) | 37.7% (30.2% - 45.1%) | 47.4% (39.1% - 55.7%) | 25.1% (18.5% - 31.6%) | 33.4% (26.5% - 40.4%) | 40.7% (32.6% - 48.8%) |
[9] | 1% | 1% | 3% | 0.4% | 0.4% | 1.2% | ||
Stable decompensated state* | >10 | HCC | 45.1% (35.1% - 55.1%) | 53.9% (42.9% - 64.9%) | 40.5% (31.5% - 49.4%) | 50.3% (39.5% - 61.1%) | ||
[9] | 2% | 4.5% | 0.6% | 1.8% | ||||
Progressive decompensated state* | Death related to liver disease | 35.6% (26.9% - 44.2%) | 44.1% (35.5% - 52.8%) | 54.5% (44.2% - 64.9%) | 27.6% (20.4% - 34.9%) | 35.3% (28.0% - 42.7%) | 45.0% (36.3% - 53.8%) | |
[8] | 15.6% | 15.6% | 15.6% | 15.6% | 15.6% | 15.6% | ||
Progressive decompensated state* | HCC | 39.1% (29.4% - 48.9%) | 48.1% (37.9% - 58.3%) | 58.9% (47.5% - 70.4%) | 31.9% (23.8% - 40.0%) | 40.7% (31.7% - 49.8%) | 51.0% (40.8% - 61.3%) | |
HCC | ≤ 1 | Death related to liver disease | 32.5% (25.6% - 39.3%) | 40.7% (33.3% - 48.2%) | 49.9% (41.5% - 58.4%) | 26.6% (18.8% - 34.5%) | 35.6% (27.5% - 43.8%) | 45.5% (36.4% - 54.6%) |
[9] | 80% | 80% | 85% | 80% | 80% | 85% | ||
HCC | > 1 | Death related to liver disease | 41.6% (33.9% - 49.3%) | 50.8% (42.5% - 59.1%) | 61.5% (52.1% - 70.9%) | 34.1% (26.1% - 42.2%) | 43.5% (35.0% - 51.9%) | 54.6% (45.1% - 64.2%) |
[9] | 35% | 35% | 35% | 35% | 35% | 35% |