Table 2 35 selected meta-analyses (15 with binary outcomes and 19 with continuous outcomes)
Meta-analysis | Experimental intervention | Comparator | Binary outcome | Continuous outcome |
|---|---|---|---|---|
1 | Platform-switched implant restoration | Platform match | - | Marginal bone loss |
2 | Scaling and root planning + antimicrobial photodynamic therapy | Scaling and root planning | - | Clinical attachment level gain |
3. | Low-level laser energy irradiation | Nonactive comparator | - | Trismus |
4.a. | Coronally advanced flap + connective tissue graft | Coronally advanced flap | Complete root coverage | Gingival recession change |
4.b. | Coronally advanced flap + enamel matrix derivative | Coronally advanced flap | Complete root coverage | Gingival recession change |
4.c. | Coronally advanced flap + acellular dermal matrix | Coronally advanced flap | Complete root coverage | Gingival recession change |
4.d. | Coronally advanced flap + barrier membranes | Coronally advanced flap + connective tissue graft | Complete root coverage | Gingival recession change |
4.e | Coronally advanced flap + acellular dermal matrix | Coronally advanced flap + connective tissue graft | Complete root coverage | Gingival recession change |
5. | Secondary closure technique | Primary closure technique | Infectious complication | Pain |
6.a | Guided tissue regeneration (rm) + bone substitutes | Subepithelial connective tissue grafts | - | Gingival recession change |
6.b | Guided tissue regeneration (rm) + bone substitutes | Guided tissue regeneration (rm) | Complete root coverage | Gingival recession change |
7. | Platelet-rich plasma | Control | - | Clinical attachment level gain |
8.a | Loading of osteointegreated implants within 1 week | Loading of osteointegreated implants after 2 months | Prosthesis failure | Marginal bone level changes |
8.b | Loading of osteointegreated implants within 1 week | Loading of osteointegreated implants between 1 week and 2 months | Prosthesis failure | Marginal bone level changes |
9. | Emdogain | Control | Probing attachment level gain < 2 mm | - |
10. | Procedure with flap elevation | Flapless implant insertion | Implant failure | - |
11. | 1-stage bonding (self-etch) | 2-stage bonding (acid-etch) | Bracket failure | - |
12. | Dental floss | Interdental brushes | - | Interproximal gingival bleeding |
13. | Antibiotic - Pre-operative prophylaxis | Placebo | - | Pain |
14. | Glass-ionomer cement | Amalgam | Caries | - |
15.a | Fluoride-containing resin-based sealant | Light-cured resin-based sealant | Complete retention | - |
15.b | Rubber dam | Cotton rolls | Complete retention | - |
16 | Guided tissue regeneration | Control | - | Clinical attachment level gain |
17. | Scaling and root planning + Diode laser | Scaling and root planning | - | Probing depth reduction |
18. | Supplemental perioperative steroids | Placebo | - | Systolic blood pressure |