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Table 2 35 selected meta-analyses (15 with binary outcomes and 19 with continuous outcomes)

From: Comparison of intervention effects in split-mouth and parallel-arm randomized controlled trials: a meta-epidemiological study

Meta-analysis Experimental intervention Comparator Binary outcome Continuous outcome
1 Platform-switched implant restoration Platform match - Marginal bone loss
2 Scaling and root planning + antimicrobial photodynamic therapy Scaling and root planning - Clinical attachment level gain
3. Low-level laser energy irradiation Nonactive comparator - Trismus
4.a. Coronally advanced flap + connective tissue graft Coronally advanced flap Complete root coverage Gingival recession change
4.b. Coronally advanced flap + enamel matrix derivative Coronally advanced flap Complete root coverage Gingival recession change
4.c. Coronally advanced flap + acellular dermal matrix Coronally advanced flap Complete root coverage Gingival recession change
4.d. Coronally advanced flap + barrier membranes Coronally advanced flap + connective tissue graft Complete root coverage Gingival recession change
4.e Coronally advanced flap + acellular dermal matrix Coronally advanced flap + connective tissue graft Complete root coverage Gingival recession change
5. Secondary closure technique Primary closure technique Infectious complication Pain
6.a Guided tissue regeneration (rm) + bone substitutes Subepithelial connective tissue grafts - Gingival recession change
6.b Guided tissue regeneration (rm) + bone substitutes Guided tissue regeneration (rm) Complete root coverage Gingival recession change
7. Platelet-rich plasma Control - Clinical attachment level gain
8.a Loading of osteointegreated implants within 1 week Loading of osteointegreated implants after 2 months Prosthesis failure Marginal bone level changes
8.b Loading of osteointegreated implants within 1 week Loading of osteointegreated implants between 1 week and 2 months Prosthesis failure Marginal bone level changes
9. Emdogain Control Probing attachment level gain < 2 mm -
10. Procedure with flap elevation Flapless implant insertion Implant failure -
11. 1-stage bonding (self-etch) 2-stage bonding (acid-etch) Bracket failure -
12. Dental floss Interdental brushes - Interproximal gingival bleeding
13. Antibiotic - Pre-operative prophylaxis Placebo - Pain
14. Glass-ionomer cement Amalgam Caries -
15.a Fluoride-containing resin-based sealant Light-cured resin-based sealant Complete retention -
15.b Rubber dam Cotton rolls Complete retention -
16 Guided tissue regeneration Control - Clinical attachment level gain
17. Scaling and root planning + Diode laser Scaling and root planning - Probing depth reduction
18. Supplemental perioperative steroids Placebo - Systolic blood pressure
  1. rm: with resorbable membranes.