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Table 1 Goal of study, overall and stratified according to whether the IPD-MA included only randomized controlled trials, or included both randomized controlled trials and observational studies 1

From: Systematic review of methods for individual patient data meta- analysis with binary outcomes

Reason Included only randomized controlled trials (n = 15) N (%) Included observational studies (n = 11) N (%) Overall N (%)
To estimate a treatment effect 10 (67%) 3 (27%) 13 (50%)
To investigate safety of a treatment 2 (13%) 1 (9%) 3 (12%)
To estimate diagnostic accuracy 1 (7%) 4 (36%) 5 (19%)
To identify predictors 1 (7%) 3 (27%) 4 (15%)
Other/Unclear 2 (13%) 1 (9%) 3 (12%)
  1. 1Numbers may not total to 100% because some IPD-MA had more than one goal.