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Table 6 Relative decrease in sample size given various scenarios for increasing the number of baseline (p) or follow-up (r) measures.

From: How many repeated measures in repeated measures designs? Statistical issues for comparative trials

pre

post

mix

Change from

Change to

Sample size reduction

   

No. of baseline measures (p)

No. of follow-up measures (r)

No. of baseline measures (p)

No. of follow-up measures (r)

 

0.7

0.7

0.5

1

1

1

4

30%

     

4

1

10%

     

4

4

40%

   

4

4

4

7

7%

     

7

4

3%

     

7

7

10%

   

7

7

7

14

5%

     

14

7

2%

     

14

14

8%

   

14

14

28

28

4%

0.5

0.5

0.5

1

1

1

4

50%

     

4

1

20%

     

4

4

70%

   

4

4

4

7

24%

     

7

4

17%

     

7

7

40%

   

7

7

7

14

27%

     

14

7

22%

     

14

14

48%

   

14

14

28

28

49%

0.9

0.9

0.8

1

1

1

4

21%

     

4

1

14%

     

4

4

35%

   

4

4

4

7

5%

     

7

4

3%

     

7

7

8%

   

7

7

7

14

3%

     

14

7

3%

     

14

14

6%

   

14

14

28

28

3%