Table 4 The overall p-value of the final analysis based on the combination of p 1 = 0.1758 and p 2 = 0.1517 (second example) in dependence of the truncation point Ď„, Ď„ = 1 corresponds to Fisher's product criterion.
From: Adaptive designs based on the truncated product method
Ď„ | p-value for TPM |
|---|---|
0.1 | 1 |
0.2 | 0.0801 |
0.3 | 0.0964 |
0.4 | 0.1064 |
0.5 | 0.1130 |
0.6 | 0.1174 |
0.7 | 0.1203 |
0.8 | 0.1221 |
0.9 | 0.1230 |
1.0 | 0.1233 |