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Table 4 Comparison of search sensitivities in three case studies

From: Identifying systematic reviews of the adverse effects of health care interventions

Search Terms

Sensitivity in DARE in this case study (GS = 256)

Sensitivity in CDSR in this case study (GS = 14)

Sensitivity in MEDLINE in Badgett et al's study [2] (QGS = 323)

Sensitivity in MEDLINE in Golder et al's study [4] (QGS = 67)

Sensitivity in EMBASE in Golder et al's study [4] (QGS = 72)

'adverse effects' (floating subheading)

77%

64%

86%

79%

79%[1]

'complications' (floating subheading)

14%

0%

12%

6%

5%[1]

'poisoning' (floating subheading)

0.4%

0%

10%

0%

n/a

'chemically induced' (floating subheading)

33%

29%

Not tested

28%

n/a

'toxicity' (floating subheading)

1%

0%

Not tested

0%

3%[1]

'drug effects' (floating subheading)

16%

29%

Not tested

33%

n/a

'adverse effects' OR 'complications' OR 'poisoning' (floating subheadings)

79%

57%

95%

82%

81%

'adverse effects OR 'complications' OR 'poisoning' OR 'drug effects' OR 'toxicity' OR 'chemically induced' (floating subheadings)

85%

64%

Not tested

88%

81%[1]

'adverse effects' OR 'drug effects' OR 'complications' OR 'poisoning' OR 'toxicity' OR 'chemically induced' (all floating subheadings) OR exp DRUG HYPERSENSITIVITY OR exp DRUG TOXICITY OR exp PRODUCT SURVEILLANCE, POSTMARKETING

85%

64%

Not tested

88%

81%[1]

exp DRUG HYPERSENSITIVITY OR exp DRUG TOXICITY OR exp PRODUCT SURVEILLANCE, POSTMARKETING

4%

0%

Not tested

10%

7%

text word 'adverse' in the title or abstract

16%[2]

29%[2]

10%

54%

50%

synonyms of 'adverse effects' in the title

52%

7%

Not tested

18%

19%

synonyms of 'adverse effects' in the abstract

45%[2]

36%[2]

Not tested

87%

89%

synonyms of 'adverse effects' in the title Or abstract

63%[2]

36%[2]

Not tested

75%

75%

  1. [1] the subheadings 'adverse drug reaction', drug toxicity' and ' complication' were used in EMBASE as nearest equivalent to 'adverse effects', 'toxicity' and 'complications'. [2] searches in DARE and CDSR were limited to sections of the structured abstracts.