From: Pooling overdispersed binomial data to estimate event rate
Treatment Arm* | Sample Size (No. of Patients – ni) | No. of Treatment Termination Due to Adverse Effect (xi) | Proportion of Treatment Termination (pi = xi/ni) |
---|---|---|---|
1 | 184 | 7 | 3.80% |
2 | 65 | 1 | 1.54% |
3 | 33 | 1 | 3.03% |
4 | 151 | 4 | 2.65% |
5 | 24 | 0 | 0.00% |
6 | 30 | 0 | 0.00% |
7 | 20 | 0 | 0.00% |
8 | 22 | 0 | 0.00% |
9 | 50 | 4 | 8.00% |
10 | 50 | 5 | 10.00% |
11 | 18 | 0 | 0.00% |
12 | 26 | 0 | 0.00% |
13 | 72 | 0 | 0.00% |
14 | 30 | 1 | 3.33% |
15 | 16 | 0 | 0.00% |
16 | 26 | 2 | 7.69% |
17 | 95 | 8 | 8.42% |
18 | 95 | 3 | 3.16% |
19 | 186 | 0 | 0.00% |
20 | 146 | 11 | 7.53% |
21 | 142 | 2 | 1.41% |
22 | 124 | 8 | 6.45% |
23 | 56 | 1 | 1.79% |
24 | 12 | 0 | 0.00% |
25 | 50 | 0 | 0.00% |
26 | 88 | 3 | 3.41% |
27 | 48 | 0 | 0.00% |
28 | 75 | 4 | 5.33% |
29 | 76 | 0 | 0.00% |
30 | 56 | 1 | 1.79% |
31 | 153 | 9 | 5.88% |
32 | 68 | 1 | 1.47% |
33 | 120 | 13 | 10.83% |
34 | 44 | 0 | 0.00% |
35 | 84 | 0 | 0.00% |
36 | 21 | 0 | 0.00% |
37 | 145 | 3 | 2.07% |
38 | 83 | 10 | 12.05% |
39 | 68 | 3 | 4.41% |
40 | 30 | 3 | 10.00% |
41 | 120 | 3 | 2.50% |