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Table 2 Methodological quality of meta-analyses.

From: Industry-supported meta-analyses compared with meta-analyses with non-profit or no support: Differences in methodological quality and conclusions

Questions

Supported by industry

Non-profit support or no support

P value*

Undeclared support

 

(N = 10)

(N = 18)

 

(N = 11)

1. Were the search methods used to find evidence on the primary question stated?

6

18

0.02

6

2. Was the search for evidence reasonably comprehensive?

4

17

<0.01

6

3. Were the criteria used for deciding which studies to include reported?

5

17

0.03

10

4. Was bias in the selection of studies avoided?

1

12

0.01

3

5. Were the criteria used for assessing the validity of the included studies reported?

3

15

0.02

5

6. Was the validity of all studies referred to in the text assessed using appropriate criteria?

1

10

0.04

1

7. Were the methods used to combine the findings of the relevant studies reported?

9

17

1.00

10

8. Were the findings of the relevant studies combined appropriately?

7

16

0.46

8

9. Were the conclusions made by the author(s) supported by the data reported?

9

15

1.00

9

Overall quality (1–7) (median score)

2.5

6

<0.01

3

  1. Number of meta-analyses that obtained an affirmative answer to the questions of the Oxman and Guyatt index; and median overall quality score.
  2. * Supported by industry vs non-profit or no support.