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Table 2 Numbers (%) of improved and deteriorated patients

From: Estimating the number needed to treat from continuous outcomes in randomised controlled trials: methodological challenges and worked example using data from the UK Back Pain Exercise and Manipulation (BEAM) trial

  Improved Stable Deteriorated
Three months       
Best care       
5 point reduction 62 (24) 181 (70) 13 (5)
30% change 125 (49) 99 (39) 32 (13)
Exercise       
5 point reduction 82 (36) 138 (61) 5 (2)
30% change 135 (60) 81 (36) 9 (4)
Spinal manipulation       
5 point reduction 125 (44) 148 (52) 14 (5)
30% change 193 (67) 63 (22) 31 (11)
Exercise and spinal manipulation       
5 point reduction 117 (45) 135 (52) 7 (3)
30% change 185 (71) 61 (24) 13 (5)
12 months       
Best care       
5 point reduction 84 (34) 148 (60) 16 (6)
30% change 139 (56) 82 (33) 27 (11)
Spinal manipulation       
5 point reduction 125 (46) 133 (49) 15 (5)
30% change 187 (68) 62 (23) 24 (9)
Exercise and spinal manipulation       
5 point reduction 115 (45) 133 (52) 9 (4)
30% change 180 (70) 57 (22) 9 (4)