Direction of association§ | Methodological Quality§ | ||
---|---|---|---|
1. Very Poor† | 2. Poor† | 3. Good | |
A. Clear evidence of positive association (i.e. increased risk) | 1A | 2A | 3A |
B. Clear evidence of negative association (i.e. protective, preventive) | 1B | 2B | 3B |
C. Absence of Evidence (i.e. H0 not rejected or wide CIs) | 1C | 2C | 3C |
D. Statistically significant association, but not clinically relevant | 1D | 2D | 3D |