Fig. 3From: Minimax and admissible adaptive two-stage designs in phase II clinical trialsFor the urothelial cancer trial with parameters (α,β,π u ,π a )=(0.1,0.2,0.35,0.5), the design parameters for Simon’s minimax design, the minimax-EF design and the proposed adaptive minimax design. The maximum sample size, n(S), is plotted as a function of the number of responses from the first stage, SBack to article page