Fig. 1
From: Modelling multiple thresholds in meta-analysis of diagnostic test accuracy studies
Bias of sensitivity and specificity at threshold 0 (top panel) and at the true optimal threshold (bottom panel). The Poisson distribution was chosen with λ=1.3 for the number of thresholds. The four plots at the bottom show the case of same standard deviations (SD), the top four plots the case of different standard deviations. The heterogeneity of the studies increases from left to right