Table 9 Simulation results from the alternative simulation approach: the estimated means, based on 500 replicates, are reported for coefficients in model (4)
From: Time-varying SMART design and data analysis methods for evaluating adaptive intervention effects
Parameter estimation | ||||||||
β 12 | β 23 | β 32 | β 42 | |||||
(first-stage intervention A 1) | (second-stage interventions for responder A 2NR ) | (time of intervention T 2) | (interaction term A 1 . A 2NR ) | |||||
True value | −0.6 | 0.5 | 0.4 | −1.5 | ||||
Joint model | Estimate | −0.608 | 0.492 | 0.447 | −1.338 | |||
MSE | 0.002 | 0.003 | 0.018 | 0.034 | ||||
CI% | 97 % | 96 % | 87 % | 70 % | ||||
Length of CI | 0.199 | 0.192 | 0.376 | 0.411 | ||||
TVMEM | Estimate | −0.534 | 0.492 | 0.448 | −2.367 | |||
MSE | 0.007 | 0.003 | 0.020 | 0.763 | ||||
CI% | 74 % | 93 % | 84 % | 0 % | ||||
Length of CI | 0.197 | 0.191 | 0.376 | 0.529 | ||||