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Table 1 Main characteristics of the data and study outcomes used for analysis

From: Methods for network meta-analysis of continuous outcomes using individual patient data: a case study in acupuncture for chronic pain

ID Study 1st author, year Location Pain group (type) Age – mean (SD) Trial follow-up period / Time point used in the analysis (months) Treatment Obser-vations HRQoL outcome mapped Pain outcome standardised
1 Diener 2006 [46] Germany Headache (migraine) 37.62 (10.4) 6 / 3 Usual care 328 SF-12 Migraine days
Sham acupuncture 202
Acupuncture 305
2 Endres 2007 [47] Germany Headache (TTH) 38.44 (11.77) 6 / 3 Sham acupuncture 200 SF-12 TTH days
Acupuncture 209
3 Jena 2008 [48] Germany Headache (headache) 43.66 (12.69) 6 / 3 Usual care 1613 SF-36 Headache days
Acupuncture 1569
4 Linde 2005 [44] Germany Headache (migraine) 42.55 (11.35) 6 / 3 Usual care 76 SF-36 Days of moderate to severe pain
Sham acupuncture 81
Acupuncture 145
5 Melchart 2005 [45] Germany Headache (TTH) 42.68 (13.18) 6 / 3 Usual care 75 SF-36 Headache days
Sham acupuncture 62
Acupuncture 132
6 Vickers 2004 [43] UK Headache (headache) 46.34 (10.39) 12 / 3 Usual care 161 SF-36 Severity score
Acupuncture 140
7 Brinkhaus 2006 [55] Germany Musculoske-letal (low back) 58.81 (9.13) 12 / 2 Usual care 79 SF-36 VAS pain score
Sham acupuncture 73
Acupuncture 146
8 Carlsson 2001 [50] Sweden Musculoske-letal (low back) 49.84 (15.4) 6 / 3 Sham acupuncture 16 VAS pain VAS pain score
Acupuncture 34
9 Guerra 2004 [53] Spain Musculoske-letal (shoulder) 59.19 (11.37) 6 / 3 Sham acupuncture 65 VAS pain VAS pain score
Acupuncture 65
10 Haake 2007 [61] Germany Musculoske-letal (low back) 50.15 (14.68) 6 / 3 Usual care 388 SF-12 Von Korff pain intensity score
Sham acupuncture 387
Acupuncture 387
11 Irnich 2001 [51] Germany Musculoske-letal (neck) NA 3 / 3 Sham acupuncture 61 VAS pain VAS pain score
Acupuncture 56
12 Kennedy 2008 [62] Northern Ireland Musculoske-letal (low back) 45.58 (11.1) 3 / 3 Sham acupuncture 24 VAS pain Roland Morris disability score
Acupuncture 24
13 Kerr 2003 [52] Northern Ireland Musculoske-letal (low back) NA 6 / 1 Sham acupuncture 20 VAS pain VAS pain score
Acupuncture 26
14 Kleinhenz 1999 [49] Germany Musculoske-letal (shoulder) NA 3 / 1 Sham acupuncture 27 CMS and predicted VAS pain CMS
Acupuncture 25
15 Salter 2006 [56] UK Musculoske-letal (neck) 47.71 (16.51) 3 / 3 Usual care 14 no mapping – EQ-5D available Northwick Park pain score
Acupuncture 10
16 Thomas 2006 [58] UK Musculoske-letal (neck) 42.62 (10.71) 24 / 3 Usual care 80 no mapping – EQ-5D available SF-36 bodily pain score
Acupuncture 159
17 Vas 2006 [57] Spain Musculoske-letal (neck) 46.73 (13.2) 6 / 1 Sham acupuncture 62 SF-36 VAS pain score
Acupuncture 61
18 Vas 2008 [63] Spain Musculoske-letal (shoulder) 55.68 (11.37) 12 / 3 Sham acupuncture 220 VAS pain CMS
Acupuncture 205
19 White 2004 [54] UK Musculoske-letal (neck) 53.36 (15.61) 12 / 3 Sham acupuncture 65 VAS pain VAS pain score
Acupuncture 70
20 Witt 2006 [59] Germany Musculoske-letal (neck) 50.57 (12.93) 6 / 3 Usual care 1698 SF-36 Neck pain and disability score
Acupuncture 1753
21 Witt 2006 [60] Germany Musculoske-letal (low back) 52.83 (13.33) 6 / 3 Usual care 1390 SF-36 Hanover functional ability score
Acupuncture 1451
22 Foster 2007 [41] UK Osteoarthritis of the knee 63.23 (8.81) 12 / 1 Usual care 116 VAS pain WOMAC pain score
Sham acupuncture 119
Acupuncture 117
23 Berman 2004 [36] USA Osteoarthritis of the knee 65.46 (8.62) 6 / 2 Usual care 189 no mapping – EQ-5D available WOMAC pain score
Sham acupuncture 191
Acupuncture 190
24 Scharf 2006 [39] Germany Osteoarthritis of the knee 62.81 (10.07) 6 / 3 Usual care 316 SF-12 WOMAC total score
Sham acupuncture 365
Acupuncture 326
25 Vas 2004 [37] Spain Osteoarthritis of the knee 67.04 (10.09) 3 / 3 Sham acupuncture 49 WOMAC total WOMAC total score
Acupuncture 48
26 Williamson 2007 [42] UK Osteoarthritis of the knee 70.67 (8.94) 3 / 3 Usual care 61 WOMAC total Oxford knee score
Acupuncture 60
27 Witt 2005 [38] Germany Osteoarthritis of the knee 64.01 (6.49) 12 / 2 Usual care 70 SF-36 WOMAC total score
Sham acupuncture 75
Acupuncture 149
28 Witt 2006 [40] Germany Osteoarthritis of the knee 61.2 (10.39) 6 / 3 Usual care 310 SF-36 WOMAC total score
Acupuncture 322