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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Accounting for parameter uncertainty in the definition of parametric distributions used to describe individual patient variation in health economic models

Fig. 1

a Exemplary plot of a Gamma distribution’s shape and scale parameters, showing their point-estimates and the 95% confidence ellipse representing the uncertainty and correlation in these estimates. b Density plot of the Gamma distribution as defined in Fig. 1a. The black line represents the density curve from which individual values are drawn in each run of the PSA if parameter uncertainty in the parameter estimates is ignored. The grey surface represents the 95% confidence interval of density curves from which individual values are drawn if different (correlated) sets of parameter values are used in each run of the PSA, i.e. if parameter uncertainty in the parameter estimates is accounted for

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