| |
Sample size
|
Event observations
|
|---|
|
Progression (Post-induction)
|
Death (Post-induction)
|
Progression (Re-induction)
|
Death (Re-induction)
|
Death (Salvage)
|
|---|
|
Subgroup 0: No Subgroups
|
558
|
519
|
39
|
370
|
109
|
410
|
|
Observation
|
279
|
270
|
9
|
200
|
54
|
216
|
|
Maintenance
|
279
|
249
|
30
|
170
|
55
|
194
|
|
Subgroup 1: SD
|
191
|
185
|
6
|
128
|
43
|
142
|
|
Observation
|
95
|
95
|
0
|
68
|
22
|
73
|
|
Maintenance
|
96
|
90
|
6
|
60
|
21
|
69
|
|
Subgroup 2: CR/PR
|
367
|
334
|
33
|
242
|
66
|
268
|
|
Observation
|
184
|
175
|
9
|
132
|
32
|
143
|
|
Maintenance
|
183
|
159
|
24
|
110
|
34
|
125
|
|
Subgroup 3: Synchronous
|
410
|
382
|
28
|
275
|
82
|
300
|
|
Observation
|
191
|
186
|
5
|
143
|
33
|
153
|
|
Maintenance
|
219
|
196
|
23
|
132
|
49
|
147
|
|
Subgroup 4: Metachronous
|
147
|
137
|
10
|
95
|
27
|
110
|
|
Observation
|
88
|
84
|
4
|
57
|
21
|
63
|
|
Maintenance
|
59
|
53
|
6
|
38
|
6
|
47
|
|
Subgroup 5: SD & Synchronous
|
141
|
136
|
5
|
94
|
34
|
102
|
|
Observation
|
67
|
67
|
0
|
49
|
15
|
52
|
|
Maintenance
|
74
|
69
|
5
|
45
|
19
|
50
|
|
Subgroup 6: SD & Metachronous
|
50
|
49
|
1
|
34
|
9
|
40
|
|
Observation
|
28
|
28
|
0
|
19
|
7
|
21
|
|
Maintenance
|
22
|
21
|
1
|
15
|
2
|
19
|
|
Subgroup 7: CR/PR & Synchronous
|
269
|
246
|
23
|
181
|
48
|
198
|
|
Observation
|
124
|
119
|
5
|
94
|
18
|
101
|
|
Maintenance
|
145
|
127
|
18
|
87
|
30
|
97
|
|
Subgroup 8: CR/PR & Metachronous
|
97
|
88
|
9
|
61
|
18
|
70
|
|
Observation
|
60
|
56
|
4
|
38
|
14
|
42
|
|
Maintenance
|
37
|
32
|
5
|
23
|
4
|
28
|
-
SD stable disease, CR/PR complete or partial response
