BMC Medical Research Methodology

Table 3 Estimated numbers of required subjects for 2, 3, 4 and 5 observations with ICC = 0.4

From: Sample size determination for mediation analysis of longitudinal data

Observations
	2			3			4			5
Effect size	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap	Sobel	Product	Bootstrap
SS	479	394	395	363	300	334	313	269	276	282	251	253
SH	379	351	564	305	299	298	276	266	270	290	244	254
SM	376	350	351	307	301	302	269	251	253	282	238	232
SL	360	361	361	293	302	305	271	276	275	283	251	264
HS	258	215	219	181	153	159	149	120	134	137	106	111
HH	143	117	123	108	90	92	91	80	88	93	72	75
HM	116	109	111	96	88	88	85	79	81	88	72	78
HL	112	109	110	93	86	90	84	79	85	86	73	74
MS	217	210	212	152	132	141	116	105	118	100	83	85
MH	88	72	81	65	54	59	56	45	48	54	39	40
MM	64	54	55	49	45	47	42	37	38	42	35	33
ML	54	49	50	45	41	44	39	38	38	41	35	40
LS	209	198	204	143	138	140	105	96	108	85	81	87
LH	68	61	63	49	42	49	40	33	37	35	28	29
LM	41	34	36	32	25	26	25	22	21	24	19	19
LL	29	24	26	23	20	23	20	18	19	20	17	18

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ISSN: 1471-2288

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