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Table 1 Reporting of recommended study design features in critical care medicine manuscripts 2005 and 2015 (binary ratings). Comparisons were made using Chi square tests (P-value) and simple logistic regression (odds ratio)

From: Animal experimental research design in critical care

Study design feature

Total (n = 825)

2005 (n = 482)

2015 (n = 343)

Bonferroni-adjusted P-value

Odds Ratio (98.3%CI)

Power analysis performed

40 (5)

10 (2)

30 (9)

< 0.0001

4.52 (1.86,11.0)

Randomization performed

330 (40)

169 (35)

161 (47)

0.0018

1.64 (1.16,2.31)

Blinding performed

218 (26)

96 (20)

122 (36)

< 0.0001

2.22 (1.51,3.25)