Study design feature | Total (n = 825) | 2005 (n = 482) | 2015 (n = 343) | Bonferroni-adjusted P-value | Odds Ratio (98.3%CI) |
---|---|---|---|---|---|
Power analysis performed | 40 (5) | 10 (2) | 30 (9) | < 0.0001 | 4.52 (1.86,11.0) |
Randomization performed | 330 (40) | 169 (35) | 161 (47) | 0.0018 | 1.64 (1.16,2.31) |
Blinding performed | 218 (26) | 96 (20) | 122 (36) | < 0.0001 | 2.22 (1.51,3.25) |