From: A descriptive analysis of non-Cochrane child-relevant systematic reviews published in 2014
Included study characteristics | Overall (n = 1598) | Type of review questiona | |||
---|---|---|---|---|---|
Therapeutic (n = 753) | Epidemiology (n = 701) | Diagnostic/ Prognostic (n = 91) | Other (n = 53) | ||
Study designs: eligible, n (%) | |||||
 Only RCTs | 203 (12.7) | 202 (26.8) | 1 (0.1) | 0 (0.0) | 0 (0.0) |
 RCTs and other designs | 765 (47.9) | 476 (63.2) | 240 (34.2) | 31 (34.1) | 18 (34.0) |
 Only non-RCTs | 472 (29.5) | 49 (6.5) | 346 (49.4) | 48 (52.7) | 29 (54.7) |
 Unclear or not reported | 158 (9.9) | 26 (3.5) | 114 (16.3) | 12 (13.2) | 6 (11.3) |
Study designs: included in the review, n (%) | |||||
 Only RCTs | 231 (14.5) | 227 (30.1) | 1 (0.1) | 0 (0.0) | 0 (0.0) |
 RCTs and other designs | 420 (26.3) | 334 (44.4) | 66 (9.4) | 13 (14.3) | 7 (13.2) |
 Only non-RCTs | 796 (49.8) | 169 (22.4) | 523 (74.6) | 71 (78.0) | 36 (67.9) |
 Not applicable (empty) | 4 (0.3) | 4 (0.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
 Unclear or not reported | 147 (9.2) | 19 (2.5) | 111 (15.8) | 7 (7.7) | 10 (18.9) |
Included studies, median (IQR) | 19 (11, 33) | 15 (9, 26) | 23 (13, 40) | 18 (12, 28) | 20 (12, 41) |
Reported on the number of participants, n (%)b | 692 (43.4) | 370 (49.4) | 273 (38.9) | 41 (45.1) | 8 (15.1) |
Included participants, median (IQR) | 2134 (648, 13,079) | 1042 (427, 3324) | 11,038 (2098, 63,897) | 1086 (515, 2831) | 2036 (1284, 5374) |
Participant type | |||||
 Children only | 628 (39.3) | 353 (46.9) | 212 (30.2) | 41 (45.1) | 25 (47.2) |
 Children and adults | 787 (49.2) | 335 (44.5) | 384 (54.8) | 46 (50.5) | 27 (50.9) |
 Pregnancy | 176 (11.0) | 65 (8.6) | 99 (14.1) | 4 (4.4) | 0 (0.0) |
 Adults onlyc | 7 (0.4) | 0 (0.0) | 6 (0.9) | 0 (0.0) | 1 (1.9) |