Table 1 Interventions received according to the 2 × 2 factorial trial design. Randomisation is 1:1 between the two topical cream arms and 1:1 for qHPV and placebo
| Â | Topical creams | ||
|---|---|---|---|
Imiquimod | Podophyllotoxin | ||
Vaccines | qHPV vaccine | Arm A n = 125 Imiquimod cream for 16 weeks; qHPV vaccine at months 0, 2 and 6 | Arm B n = 125 Podophyllotoxin cream for 4 weeks; qHPV vaccine at months 0, 2 and 6 |
Saline, placebo control | Arm C n = 125 Imiquimod cream for 16 weeks; placebo vaccine at months 0, 2 and 6 | Arm D n = 125 Podophyllotoxin cream for 4 weeks; placebo vaccine at months 0, 2 and 6. | |