Table 1 Modified Preventability Algorithm [24]
From: Methods for evaluating adverse drug event preventability in emergency department patients
Definitely Preventable ADE | |
1. Was there a history of allergy or previous reactions to the drug or drug class? | Yes/No/Uncertain |
-If yes, was the re exposure inappropriate?a* | Yes/No/Uncertain |
2. Was any drug involved inappropriate for the patient’s clinical condition?a | Yes/No/Uncertain |
3. Was the dose, route or frequency of administration inappropriate for the patient’s age, weight or disease state?a | Yes/No/Uncertain |
4.Was a toxic serum drug concentration (or laboratory monitoring test) documented?a | Yes/No/Uncertain |
5. Was there a known treatment for the ADE? (eg. To prevent predictable drug side effects)a | Yes/No/Uncertain |
Probably Preventable ADE | |
6. Was required therapeutic drug monitoring or other necessary tests not performed?b | Yes/No/Uncertain |
7. Was a drug interaction involved in the ADE?b | Yes/No/Uncertain |
8. Was poor compliance involved in the ADE?b | Yes/No/Uncertain |
9. Were preventative measures not prescribed or administered to the patient? (eg. Untreated indication?) | Yes/No/Uncertain |
-If yes, were preventative measures not contraindicated?b* | Yes/No/Uncertain |
Additional Criteria for ADE Preventability | |
10. Was there an error in ADE diagnosis that contributed to the event persisting/getting worse?a* | Yes/No/Uncertain |
11. Was there a delay in ADE diagnosis that contributed to the event persisting/getting worse?b* | Yes/No/Uncertain |
12. Was there a failure to act on the result of monitoring or testing?a* | Yes/No/Uncertain |
13. Were there errors in the transcription of the culprit drug(s) order?a* | Yes/No/Uncertain |
14. Were there any errors in dispensing of the culprit drug(s) order?a* | Yes/No/Uncertain |
15. Were there any errors in the administration of the culprit drug(s)?a* | Yes/No/Uncertain |
16. Was a superior alternative treatment available (without contraindication) that is less likely to cause an ADE?b* | Yes/No/Uncertain |
17. Was there any failure in communication that contributed to the ADE?a* | Yes/No/Uncertain |
18. Was there any equipment failure that contributed to the ADE?a* | Yes/No/Uncertain |
Automated preventability assessment based on algorithm | Definitely/Probably/Not |