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Table 6 Questions in the algorithm-based approach for which a YES answer automatically resulted in a definitely preventable rating without the option of modifying it to probably preventable

From: Methods for evaluating adverse drug event preventability in emergency department patients

Schmock and Thornton algorithm questions (response) Frequency, n (%)
n = 508
Was there a history of allergy or previous reactions to the drug or drug class? (YES) Was the re-exposure appropriate? (NO) 148 (29.1)
Was a toxic serum drug concentration (or laboratory monitoring test) documented? (YES) 144 (28.4)
Was any drug involved inappropriate for the patient’s clinical condition? (YES) 78 (15.4)
Was the dose, route or frequency of administration inappropriate for the patient’s age, weight or disease state? (YES) 66 (13.0)
Was there a known treatment for the ADE? (e.g., to prevent predictable drug side effects?) (YES) Was a known treatment not prescribed or administered to the patient? (YES) Was the known treatment contraindicated? (NO) 38 (7.5)
Was there any failure in communication that contributed to the ADE? (YES) 17 (3.4)
Was there a failure to act on the results of monitoring or testing? (YES) 11 (2.2)
Were there any errors in the administration of the culprit drug(s)? (YES) 5 (1.0)
Was there an error in ADE diagnosis that contributed to the event persisting/getting worse? (YES) 1 (0.2)