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Table 3 Correlation between sergroup-polysaccharide specific IgG levels and functional antibody titers (rSBA) in saliva measured before (T0), one month (T1) and one year (T2) after the vaccination

From: Use of saliva to monitor meningococcal vaccine responses: proposing a threshold in saliva as surrogate of protection

Serogroup

T0 R (95% CI), p-value

T1 R (95% CI), p-value

T2 R (95% CI), p-value

All R (95% CI), p-value

MenA

0.11 (āˆ’ā€‰0.03ā€“.025), 0.11

0.11 (āˆ’ā€‰0.03ā€“0.24), 0.13

0.06 (āˆ’ā€‰0.08ā€“0.20), 0.42

0.36 (0.28ā€“0.42), <ā€‰0.001

MenC

0.37 (0.29ā€“0.45), <ā€‰0.001

0.54 (0.47ā€“0.61), <ā€‰0.001

0.53 (0.46ā€“0.60), <ā€‰0.001

0.85 (0.84ā€“0.87), <ā€‰0.001

MenW

0.06 (āˆ’ā€‰0.08ā€“0.20), 0.37

0.16 (0.02ā€“0.29), 0.02

0.25 (0.11ā€“0.37), 0.001

0.60 (0.54ā€“0.65), <ā€‰0.001

MenY

0.02 (āˆ’0.12ā€“0.15), 0.82

0.09 (āˆ’ā€‰0.05ā€“0.23), 0.19

0.19 (0.05ā€“0.32), 0.007

0.76 (0.72ā€“0.79), <ā€‰0.001

  1. Note. Abbreviations: R Pearson correlation coefficient, CI confidence interval