BMC Medical Research Methodology

Table 2 Results for the simulation 2(a): outcome variables were measured on all three time-points

From: Efficient two-step multivariate random effects meta-analysis of individual participant data for longitudinal clinical trials using mixed effects models

	N = 5		N = 10		N = 15
	τ² = 0.10	τ² = 0.20	τ² = 0.10	τ² = 0.20	τ² = 0.10	τ² = 0.20
μ₂ = 0.14
Mean	0.141	0.144	0.141	0.144	0.145	0.143
SE	0.694	0.709	0.694	0.709	0.564	0.565
\( \widehat{\mathrm{SE}} \)	0.680	0.692	0.680	0.692	0.553	0.562
Coverage Rate	0.946	0.947	0.946	0.947	0.947	0.950
Power	0.061	0.057	0.061	0.057	0.059	0.057
μ₄ = 0.83
Mean	0.828	0.831	0.828	0.831	0.832	0.833
SE	0.306	0.323	0.306	0.323	0.252	0.268
\( \widehat{\mathrm{SE}} \)	0.307	0.325	0.307	0.325	0.251	0.265
Coverage Rate	0.951	0.950	0.951	0.950	0.948	0.947
Power	0.773	0.725	0.773	0.725	0.912	0.877
μ₅ = −0.46
Mean	−0.459	−0.458	−0.459	−0.458	−0.461	−0.460
SE	0.104	0.143	0.104	0.143	0.084	0.117
\( \widehat{\mathrm{SE}} \)	0.103	0.143	0.103	0.143	0.084	0.117
Coverage Rate	0.944	0.947	0.944	0.947	0.949	0.949
Power	0.992	0.890	0.992	0.890	1.000	0.976
μ₇ = 0.14
Mean	0.142	0.141	0.142	0.141	0.138	0.140
SE	0.163	0.193	0.163	0.193	0.134	0.157
\( \widehat{\mathrm{SE}} \)	0.163	0.192	0.163	0.192	0.133	0.157
Coverage Rate	0.947	0.948	0.947	0.948	0.947	0.951
Power	0.140	0.115	0.140	0.115	0.181	0.146
μ₉ = 0.05
Mean	0.051	0.050	0.051	0.050	0.048	0.050
SE	0.101	0.140	0.101	0.140	0.082	0.116
\( \widehat{\mathrm{SE}} \)	0.100	0.141	0.100	0.141	0.082	0.116
Coverage Rate	0.944	0.945	0.944	0.945	0.947	0.947
Power	0.091	0.071	0.091	0.071	0.091	0.076
μ₁₀ = −0.06
Mean	−0.061	−0.058	−0.061	− 0.058	− 0.060	−0.061
SE	0.106	0.145	0.106	0.145	0.087	0.119
\( \widehat{\mathrm{SE}} \)	0.105	0.145	0.105	0.145	0.086	0.119
Coverage Rate	0.945	0.944	0.945	0.944	0.945	0.947
Power	0.096	0.074	0.096	0.074	0.110	0.084

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ISSN: 1471-2288

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