Skip to main content

Table 2 Results for the simulation 2(a): outcome variables were measured on all three time-points

From: Efficient two-step multivariate random effects meta-analysis of individual participant data for longitudinal clinical trials using mixed effects models

  N = 5 N = 10 N = 15
τ2 = 0.10 τ2 = 0.20 τ2 = 0.10 τ2 = 0.20 τ2 = 0.10 τ2 = 0.20
μ2 = 0.14
 Mean 0.141 0.144 0.141 0.144 0.145 0.143
 SE 0.694 0.709 0.694 0.709 0.564 0.565
\( \widehat{\mathrm{SE}} \) 0.680 0.692 0.680 0.692 0.553 0.562
 Coverage Rate 0.946 0.947 0.946 0.947 0.947 0.950
 Power 0.061 0.057 0.061 0.057 0.059 0.057
μ4 = 0.83
 Mean 0.828 0.831 0.828 0.831 0.832 0.833
 SE 0.306 0.323 0.306 0.323 0.252 0.268
\( \widehat{\mathrm{SE}} \) 0.307 0.325 0.307 0.325 0.251 0.265
 Coverage Rate 0.951 0.950 0.951 0.950 0.948 0.947
 Power 0.773 0.725 0.773 0.725 0.912 0.877
μ5 = −0.46
 Mean −0.459 −0.458 −0.459 −0.458 −0.461 −0.460
 SE 0.104 0.143 0.104 0.143 0.084 0.117
\( \widehat{\mathrm{SE}} \) 0.103 0.143 0.103 0.143 0.084 0.117
 Coverage Rate 0.944 0.947 0.944 0.947 0.949 0.949
 Power 0.992 0.890 0.992 0.890 1.000 0.976
μ7 = 0.14
 Mean 0.142 0.141 0.142 0.141 0.138 0.140
 SE 0.163 0.193 0.163 0.193 0.134 0.157
\( \widehat{\mathrm{SE}} \) 0.163 0.192 0.163 0.192 0.133 0.157
 Coverage Rate 0.947 0.948 0.947 0.948 0.947 0.951
 Power 0.140 0.115 0.140 0.115 0.181 0.146
μ9 = 0.05
 Mean 0.051 0.050 0.051 0.050 0.048 0.050
 SE 0.101 0.140 0.101 0.140 0.082 0.116
\( \widehat{\mathrm{SE}} \) 0.100 0.141 0.100 0.141 0.082 0.116
 Coverage Rate 0.944 0.945 0.944 0.945 0.947 0.947
 Power 0.091 0.071 0.091 0.071 0.091 0.076
μ10 = −0.06
 Mean −0.061 −0.058 −0.061 − 0.058 − 0.060 −0.061
 SE 0.106 0.145 0.106 0.145 0.087 0.119
\( \widehat{\mathrm{SE}} \) 0.105 0.145 0.105 0.145 0.086 0.119
 Coverage Rate 0.945 0.944 0.945 0.944 0.945 0.947
 Power 0.096 0.074 0.096 0.074 0.110 0.084